PROTECTION AGAINST HANTAVIRUS INFECTION BY DAMS IMMUNITY TRANSFERRED VERTICALLY TO NEONATES

被引：19

作者：

DOHMAE, K ^{[1
]}

NISHIMUNE, Y ^{[1
]}

机构：

[1] OSAKA UNIV, MICROBIAL DIS RES INST, SUITA, OSAKA 565, JAPAN

来源：

ARCHIVES OF VIROLOGY | 1995年 / 140卷 / 01期

关键词：

D O I：

10.1007/BF01309731

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antibodies to hantavirus, Seoul type B-1 strain. vertically transferred to rat neonates prevented lethal as well as persistent infection. When relatively high titer viruses were inoculated into neonates, the mother's antibodies protected all the neonates from lethal virus infection. However, the antibodies could not protect all of the neonates from persistent infection but only half of them underwent persistent infection. The other half was completely cured but also became persistently infected when rechallenged with the active viruses after reaching maturity.

引用

页码：165 / 172

页数：8

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