EFFECTS OF HYPOTHERMIA ON TESTICULAR ISCHEMIA

被引:70
作者
MILLER, DC [1 ]
PERON, SE [1 ]
KECK, RW [1 ]
KROPP, KA [1 ]
机构
[1] MED COLL OHIO,DIV UROL,CS 10008,TOLEDO,OH 43699
关键词
D O I
10.1016/S0022-5347(17)40180-7
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The ischemic effects of prolonged testicular torsion have been well documented; however, prevention or arrest of the damaging effects of prolonged ischemia has been incompletely studied. Two groups of Sprague-Dawley rats were subjected to varying lengths of bilateral testicular ischemia. Group I underwent normothermic ischemia for two, four, and six hours. Likewise, Group II underwent similar time periods of ischemia, however, after thirty minutes of normothermic ischemia the scrotum of each animal was placed into an ice bath maintained at 4C. Two weeks postoperatively, bilateral orchiectomy was performed. Histology of the testes of the two groups was compared. Neither group revealed significant destruction of the germinal epithelium after two hours of ischemia. Group I revealed only 25% preservation of the germinal epithelium at four hours and only 8% preservation at six hours of ischemia. In contrast, Group II which received ice showed 90% preservation of germinal epithelium at four hours and 85% preservation at six hours of ischemia. We conclude that external ice application significantly preserves seminiferous tubules at four and six hours of ischemic injury in the rat testicle.
引用
收藏
页码:1046 / 1048
页数:3
相关论文
共 13 条
[1]   THE FATE OF THE HUMAN TESTES FOLLOWING UNILATERAL TORSION OF THE SPERMATIC CORD [J].
ANDERSON, JB ;
WILLIAMSON, RCN .
BRITISH JOURNAL OF UROLOGY, 1986, 58 (06) :698-704
[2]  
BARKER K., 1964, BRIT J UROL, V36, P35, DOI 10.1111/j.1464-410X.1964.tb09477.x
[3]  
Carrel A, 1908, J AMER MED ASSOC, V51, P1662
[4]   QUANTITATIVE-EVALUATION OF TESTICULAR BIOPSIES FROM MEN WITH UNILATERAL TORSION OF SPERMATIC CORD [J].
CHAKRABORTY, J ;
HIKIM, APS ;
JHUNJHUNWALA, JS .
UROLOGY, 1985, 25 (02) :145-150
[5]  
HUMPHRIES AL, 1982, BASIC CONCEPTS ORGAN, P7
[6]   TESTES AFTER TORSION [J].
KRARUP, T .
BRITISH JOURNAL OF UROLOGY, 1978, 50 (01) :43-46
[7]  
MANAX WG, 1968, HUMAN TRANSPLANTATIO, P675
[8]  
MARSHALL VC, 1984, KIDNEY TRNASPLANTATI, P134
[9]  
PERON SE, 1984, SURG FORUM, V35, P630
[10]  
POPOVIC V, 1974, HYPOTHERMIA BIOL MED, P214