AGE AND THE RATE OF INDUCTION OF ARYL-HYDROCARBON HYDROXYLASE IN ISOLATED PERIPHERAL-BLOOD MONOCYTES

被引：7

作者：

GEORGE, G ^{[1
]}

WYNNE, H ^{[1
]}

WOODHOUSE, K ^{[1
]}

机构：

[1] UNIV NEWCASTLE UPON TYNE,WOLFSON UNIT CLIN PHARMACOL,NEWCASTLE TYNE NE1 7RU,TYNE & WEAR,ENGLAND

来源：

AGE AND AGEING | 1991年 / 20卷 / 06期

关键词：

D O I：

10.1093/ageing/20.6.421

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

We have measured the rate of induction of the microsomal monooxygenase enzyme aryl hydrocarbon hydroxylase (AHH) in isolated peripheral blood monocytes from young and elderly donors. There was no effect of age on rate of induction. The mechanisms underlying impaired induction of drug metabolism in elderly people remain to be clarified.

引用

页码：421 / 423

页数：3

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