DIMINISHED AGONIST-STIMULATED INOSITOL TRISPHOSPHATE GENERATION BLOCKS STIMULUS-SECRETION COUPLING IN MOUSE PANCREATIC ACINI DURING DIET-INDUCED EXPERIMENTAL PANCREATITIS

被引：56

作者：

POWERS, RE

SALUJA, AK

HOULIHAN, MJ

STEER, ML

机构：

[1] BETH ISRAEL HOSP,DEPT SURG,330 BROOKLINE AVE,BOSTON,MA 02115

[2] BETH ISRAEL HOSP,DANA RES LABS,BOSTON,MA 02115

[3] HARVARD UNIV,HARVARD DIGEST DIS CTR,BOSTON,MA 02115

[4] HARVARD UNIV,SCH MED,BOSTON,MA 02115

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1986年 / 77卷 / 05期

关键词：

D O I：

10.1172/JCI112484

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：1668 / 1674

页数：7

共 47 条

[1]

APPERT HE, 1981, CELL TISSUE RES, V220, P673

[2] AMYLASES, ALPHA AND BETA [J].

BERNFELD, P .

METHODS IN ENZYMOLOGY, 1955, 1 :149-158

[3] INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL AS 2ND MESSENGERS [J].

BERRIDGE, MJ .

BIOCHEMICAL JOURNAL, 1984, 220 (02) :345-360

[4] RAPID ACCUMULATION OF INOSITOL TRISPHOSPHATE REVEALS THAT AGONISTS HYDROLYZE POLYPHOSPHOINOSITIDES INSTEAD OF PHOSPHATIDYLINOSITOL [J].

BERRIDGE, MJ .

BIOCHEMICAL JOURNAL, 1983, 212 (03) :849-858

[5] ACTIVATION OF PROTEIN-KINASE ACTIVITY IN PANCREATIC ACINI BY CALCIUM AND CAMP [J].

BURNHAM, DB ;

WILLIAMS, JA .

AMERICAN JOURNAL OF PHYSIOLOGY, 1984, 246 (05) :G500-G508

[6]

BURNHAM DB, 1984, J PEDIATR GASTROE S1, V3

[7]

CHENG Y, 1973, BIOCHEM PHARMACOL, V22, P3099

[8]

DEHAYE JP, 1984, J BIOL CHEM, V259, P294

[9] SYNERGISTIC EFFECT OF A23187 AND A PHORBOL ESTER ON AMYLASE SECRETION FROM RABBIT PANCREATIC ACINI [J].

DEPONT, JJHHM ;

FLEURENJAKOBS, AMM .

FEBS LETTERS, 1984, 170 (01) :64-68

[10] ETHIONINE CARCINOGENESIS [J].

FARBER, E .

ADVANCES IN CANCER RESEARCH, 1963, 7 :383-474

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