OPTICALLY-ACTIVE BICYCLO[2.2.2]OCTANE DERIVATIVES - SYNTHESIS OF (1S,4R,6R)-6-HYDROXYBICYCLO[2.2.2]OCTAN-2-ONE FROM ITS ENANTIOMER

被引：16

作者：

ALMQVIST, F

FREJD, T

机构：

[1] Organic Chemistry 1, Chemical Center, Lund University, S-221 00 Lund

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 04期

关键词：

D O I：

10.1016/0957-4166(95)00105-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(1S, 4R, 6R)-6-Hydroxybicyclo[2.2.2]octan-2-one, (+)-1, is synthesized from its enantiomer in 6 steps using a combination of orthogonal protecting groups and red-ox chemistry.

引用

页码：957 / 960

页数：4

共 13 条

[1]

ALMQVIST E, 1993, SYNTHETIC COMMUN, P1499

[2]

DAVIES HG, 1989, BIOTRANSFORMATIONS

[3]

Greene T. W., 1991, PROTECTIVE GROUPS OR

[4] PREPARATION AND SYNTHETIC UTILITY OF TERT-BUTYLDIPHENYLSILYL ETHERS [J].

HANESSIAN, S ;

LAVALLEE, P .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1975, 53 (19) :2975-2977

[5]

JONES JB, 1976, BIOTRANSFORMATIONS

[6]

MANCUSO AJ, 1981, SYNTHESIS-STUTTGART, P165

[7]

MORI K, 1992, B SOC CHIM BELG, V101, P393

[8]

MORI K, 1994, SYNTHESIS-STUTTGART, P417

[9]

MORI K, 1993, SYNTHESIS-STUTTGART, P406

[10]

MORI K, 1990, BIOCATALYSIS, V3, P25

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