THE EFFECT OF IMMUNE MEDIATORS (CYTOKINES) ON THE RELEASE OF ENDOTHELIUM-DERIVED RELAXING FACTOR (EDRF) AND OF PROSTACYCLIN BY FRESHLY HARVESTED ENDOTHELIAL-CELLS

被引：9

作者：

DUDEK, R

KIBIRA, S

KAHLER, J

BING, RJ

机构：

[1] Huntington Medical Research Institutes Department of Experimental Cardiology Pasadena

来源：

LIFE SCIENCES | 1992年 / 50卷 / 12期

关键词：

D O I：

10.1016/0024-3205(92)90205-4

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The effect of recombinant tumor necrosis factor and other cytokines stimulated by LPS (lipopolysaccharide), on the release of endothelial-derived relaxing factor and of prostacyclin was investigated using freshly harvested endothelial cells attached to plastic microcarrier beads. The results show that the cytokines failed to interfere with the release of EDRF and prostacyclin under the conditions of these experiments.

引用

收藏

页码：863 / 873

页数：11

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