METABOLISM OF C-14 1-NITROPYRENE INVIVO IN THE RAT AND MUTAGENICITY OF URINARY METABOLITES

被引：76

作者：

BALL, LM ^{[1
]}

KOHAN, MJ ^{[1
]}

INMON, JP ^{[1
]}

CLAXTON, LD ^{[1
]}

LEWTAS, J ^{[1
]}

机构：

[1] US EPA,HLTH EFFECTS RES LAB,DIV GENET TOXICOL,GENET BIOASSAY BRANCH,RES TRIANGLE PK,NC 27711

来源：

CARCINOGENESIS | 1984年 / 5卷 / 12期

关键词：

D O I：

10.1093/carcin/5.12.1557

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1557 / 1564

页数：8

共 32 条

[1] METHODS FOR DETECTING CARCINOGENS AND MUTAGENS WITH SALMONELLA-MAMMALIAN-MICROSOME MUTAGENICITY TEST [J].

AMES, BN ;

MCCANN, J ;

YAMASAKI, E .

MUTATION RESEARCH, 1975, 31 (06) :347-363

[2]

BALL LM, 1983, EXTRAHEPATIC DRUG ME, P295

[3] METABOLISM OF POLYCYCLIC COMPOUNDS .23. METABOLISM OF PYRENE IN RATS + RABBITS [J].

BOYLAND, E ;

SIMS, P .

BIOCHEMICAL JOURNAL, 1964, 90 (02) :391-&

[4]

CLAXTON LD, 1982, ENVIRON INT, V5, P389

[5] OXIDATION OF CARCINOGENIC HYDROCARBONS BY OSMIUM TETROXIDE [J].

COOK, JW ;

SCHOENTAL, R .

JOURNAL OF THE CHEMICAL SOCIETY, 1948, (FEB) :170-173

[6] A STUDY OF CHEMICAL CARCINOGENESIS .55. THE ROLE OF INTESTINAL MICROFLORA IN THE METABOLIC REDUCTION OF 1-NITROPYRENE TO 1-AMINOPYRENE IN CONVENTIONAL AND GERMFREE-RATS AND IN HUMANS [J].

ELBAYOUMY, K ;

SHARMA, C ;

LOUIS, YM ;

REDDY, B ;

HECHT, SS .

CANCER LETTERS, 1983, 19 (03) :311-316

[7]

ELBAYOUMY K, 1983, CANCER RES, V43, P3132

[8]

FOUTS JR, 1957, J PHARMACOL EXP THER, V119, P197

[9] REDUCTION OF NITROBENZOIC ACIDS IN RAT [J].

GARDNER, DM ;

RENWICK, AG .

XENOBIOTICA, 1978, 8 (11) :679-690

[10] PARTICIPATION OF CYTOCHROME-P-450 IN THE REDUCTION OF NITRO-COMPOUNDS BY RAT-LIVER MICROSOMES [J].

HARADA, N ;

OMURA, T .

JOURNAL OF BIOCHEMISTRY, 1980, 87 (05) :1539-1554

← 1 2 3 4 →