DELTA-9-TETRAHYDROCANNABINOL SHOWS ANTISPASTIC AND ANALGESIC EFFECTS IN A SINGLE CASE DOUBLE-BLIND TRIAL

被引：81

作者：

MAURER, M

HENN, V

DITTRICH, A

HOFMANN, A

机构：

[1] UNIV ZURICH,NEUROL KLIN & POLIKLIN,FRAUENKLIN STR 26,CH-8006 ZURICH,SWITZERLAND

[2] PSYCHOL INST BERATUNG & FORSCHUNG,PSIN,CH-8032 ZURICH,SWITZERLAND

[3] UNIV ZURICH,INST PHARMAKOL,CH-8006 ZURICH,SWITZERLAND

来源：

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE | 1990年 / 240卷 / 01期

关键词：

Analgesia; Delta-9-tetrahydrocannabinol; Spasticity; Spinal cord injury;

D O I：

10.1007/BF02190083

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A double-blind study was performed comparing 5 mg delta-9-tetrahydrocannabinol (THC) p.o., 50 mg codeine p.o., and placebo in a patient with spasticity and pain due to spinal cord injury. The three conditions were applied 18 times each in a randomized and balanced order. Delta-9-THC and codeine both had an analgesic effect in comparison with placebo. Only delta-9-THC showed a significant beneficial effect on spasticity. In the dosage of THC used no altered consciousness occurred. © 1990 Springer-Verlag.

引用

页码：1 / 4

页数：4

共 13 条

[1] AN APPROACH TO THE EVALUATION OF DRUG EFFECT DURING PSYCHOTHERAPY - A DOUBLE-BLIND-STUDY OF A SINGLE CASE [J].