HEMODYNAMIC-CHANGES IN ELDERLY HYPERTENSIVE PATIENTS

被引：16

作者：

SAFAR, ME

机构：

[1] Department of Internal Medicine and INSERM (U 337), Broussais Hospital, Paris

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1993年 / 6卷 / 03期

关键词：

SYSTOLIC HYPERTENSION; LARGE ARTERIES; WAVE REFLECTIONS; ELDERLY;

D O I：

10.1093/ajh/6.3.20S

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Hypertension in the elderly is characterized by a disproportionate increase of systolic blood pressure over diastolic blood pressure. Subsequently, in this category of patients, the increase in pulse pressure predominates over the increase in mean arterial pressure, thus highlighting the role of arterial changes in this pattern of hemodynamics. In the presence of normal or reduced cardiac function, the disproportionate increase in systolic pressure is the result of a combination of increases of both arterial stiffness and wave reflections. The former is primarily due to central aortic structural changes with a small contribution by modifications of the smooth muscle tone of the central large arteries. The latter is secondary to the geometric modifications of the arterial system associated with age that are responsible for the increase in wave reflections within the thoracic aorta as a consequence of increases in pulse wave velocity and in reflection points closer to the heart.

引用

页码：S20 / S23

页数：4

共 15 条

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