COMPARATIVE PHARMACOKINETICS AND SUBACUTE TOXICITY OF DI(2-ETHYLHEXYL) PHTHALATE (DEHP) IN RATS AND MARMOSETS - EXTRAPOLATION OF EFFECTS IN RODENTS TO MAN

被引：96

作者：

RHODES, C

ORTON, TC

PRATT, IS

BATTEN, PL

BRATT, H

JACKSON, SJ

ELCOMBE, CR

机构：

[1] ICI PLC,DIV PHARMACEUT,MACCLESFIELD SK10 4JT,CHESHIRE,ENGLAND

[2] NATL UNIV IRELAND UNIV COLL DUBLIN,DEPT PHARMACOL,DUBLIN 4,IRELAND

来源：

ENVIRONMENTAL HEALTH PERSPECTIVES | 1986年 / 65卷

关键词：

D O I：

10.2307/3430197

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

引用

页码：299 / 308

页数：10

共 35 条

[1] METABOLISM OF DIETHYLHEXYL PHTHALATE BY RATS ISOLATION AND CHARACTERIZATION OF URINARY METABOLITES [J].

ALBRO, PW ;

THOMAS, R ;

FISHBEIN, L .

JOURNAL OF CHROMATOGRAPHY, 1973, 76 (02) :321-330

[2] CHROMATOGRAPHIC-SEPARATION AND QUANTITATIVE-DETERMINATION OF THE METABOLITES OF DI-(2-ETHYLHEXYL) PHTHALATE FROM URINE OF LABORATORY-ANIMALS [J].

ALBRO, PW ;

JORDAN, ST ;

SCHROEDER, JL ;

CORBETT, JT .

JOURNAL OF CHROMATOGRAPHY, 1982, 244 (01) :65-79

[3] PHARMACOKINETICS, INTERACTIONS WITH MACROMOLECULES AND SPECIES-DIFFERENCES IN METABOLISM OF DEHP [J].

ALBRO, PW ;

CORBETT, JT ;

SCHROEDER, JL ;

JORDAN, S ;

MATTHEWS, HB .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1982, 45 (NOV) :19-25

[4]

ALBRO PW, 1981, DRUG METAB DISPOS, V9, P223

[5]

BEERS RF, 1952, J BIOL CHEM, V195, P133

[6] FATTY-ACID OXIDATION BY HUMAN-LIVER PEROXISOMES [J].

BRONFMAN, M ;

INESTROSA, NC ;

LEIGHTON, F .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1979, 88 (03) :1030-1036

[7]

CARPENTER CP, 1953, AMA ARCH IND HYG OCC, V8, P219

[8] REVIEW OF THE HEPATIC RESPONSE TO HYPOLIPEMIC DRUGS IN RODENTS AND ASSESSMENT OF ITS TOXICOLOGICAL SIGNIFICANCE TO MAN [J].

COHEN, AJ ;

GRASSO, P .

FOOD AND COSMETICS TOXICOLOGY, 1981, 19 (05) :585-605

[9] ABSORPTION, METABOLISM AND TISSUE DISTRIBUTION OF DI(2-ETHYLHEXYL)PHTHALATE IN RATS [J].

DANIEL, JW ;

BRATT, H .

TOXICOLOGY, 1974, 2 (01) :51-65

[10]

DANIKEN AV, 1984, TOXICOL APPL PHARM, V73, P373

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