AN ENHANCED MURINE MODEL FOR STUDIES OF SERPULINA (TREPONEMA) HYODYSENTERIAE PATHOGENESIS

被引：18

作者：

NIBBELINK, SK ^{[1
]}

WANNEMUEHLER, MJ ^{[1
]}

机构：

[1] IOWA STATE UNIV SCI & TECHNOL,VET MED RES INST,DEPT MICROBIOL IMMUNOL & PREVENT MED,AMES,IA 50011

来源：

INFECTION AND IMMUNITY | 1992年 / 60卷 / 08期

关键词：

D O I：

10.1128/IAI.60.8.3433-3436.1992

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A defined diet was used to increase the susceptibility of mice to Serpulina hyodysenteriae. BALB/cByJ, C3H/HeN, and C3H/HeJ mice, when fed the defined diet 7 to 14 days prior to and throughout the challenge period, consistently showed higher incidences of disease than mice maintained on normal rodent chow. The use of this defined diet will increase the consistency of in vivo studies following infection with S. hyodysenteriae in the mouse model.

引用

页码：3433 / 3436

页数：4

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