A NOVEL BICYCLIC ORTHOESTER AS A CHIRAL AUXILIARY - APPLICATION TO THE SYNTHESIS OF ALPHA-HYDROXY ACIDS

被引：13

作者：

DUBE, D

DESCHENES, D

TWEDDELL, J

GAGNON, H

CARLINI, R

机构：

[1] Merck Frosst Centre For Therapeutic Research, Pointe Claire-Dorval, Que. H9R 4P8

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 11期

关键词：

D O I：

10.1016/0040-4039(95)00154-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral alpha-keto orthoesters derived from tartaric acid can be reduced diastereoselectively. Hydrolysis affords optically active alpha-hydroxy acids and the recovered auxiliary.

引用

页码：1827 / 1830

页数：4

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