INTRAMOLECULAR AND INTERMOLECULAR ALPHA-SULFAMIDOALKYLATION REACTIONS

被引：40

作者：

LEE, CH ^{[1
]}

KOHN, H ^{[1
]}

机构：

[1] UNIV HOUSTON,DEPT CHEM,HOUSTON,TX 77204

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 25期

关键词：

D O I：

10.1021/jo00312a013

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The utility of α-sulfamidoalkylation processes for the generation of sulfamides has been examined. Select aryl-substituted sulfamides were prepared and then treated with acid. Both intra- and intermolecular a-sulf-amidoalkylation transformations were observed to proceed in moderate to good yields. The pathways for these reactions are discussed. The generality of these processes has been demonstrated using N,N’-di(aryl-substi-tuted)sulfamides and the utility of these reactions was examined for the preparation of cyclic sulfamides of novel structure. © 1990, American Chemical Society. All rights reserved.

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页码：6098 / 6104

页数：7

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