FACILE RADICAL DECARBOXYLATIVE ALKYLATION OF HETEROAROMATIC BASES USING CARBOXYLIC-ACIDS AND TRIVALENT IODINE COMPOUNDS

被引：63

作者：

TOGO, H

AOKI, M

YOKOYAMA, M

机构：

[1] Department of Chemistry, Faculty of Science, Chiba University, Chiba, 260

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 45期

关键词：

D O I：

10.1016/0040-4039(91)80221-Q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Many kinds of heteroaromatic bases were easily alkylated by the reaction of carboxylic acids with [bis(trifluoroacetoxy)iodo]benzene or [bis(trifluoroacetoxy)iodo]pentafluorobenzene via radical decarboxylative pathways. This system was further applied to the reaction with tetrahydrofurylcarboxylic acid, 1-(2,3,5-tri-O-benzyl)-D-ribofuranosylacetic acid, and 1-(2,3,5-tri-O-benzyl)-D-fibofuranosylcarboxylic acid for the model synthesis of C-nucleosides.

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收藏

页码：6559 / 6562

页数：4

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