LOCALIZED C-13 NMR-SPECTROSCOPY OF MYOINOSITOL IN THE HUMAN BRAIN INVIVO

被引：39

作者：

GRUETTER, R

ROTHMAN, DL

NOVOTNY, EJ

SHULMAN, RG

机构：

[1] YALE UNIV,SCH MED,DEPT INTERNAL MED,NEW HAVEN,CT 06510

[2] YALE UNIV,SCH MED,DEPT PEDIAT,NEW HAVEN,CT 06510

来源：

MAGNETIC RESONANCE IN MEDICINE | 1992年 / 25卷 / 01期

关键词：

D O I：

10.1002/mrm.1910250121

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Natural abundance 13C NMR spectra obtained from 144‐cm3volumes in the human brain contained well‐resolved resonances of myo‐inositol after 60 min of data accumulation. A mean concentration of 7.2 ± 0.5 pmol/g (±SE, n = 7) was calculated from the comparison with phantoms. 13C NMR spectroscopy thus provides a complementaryrole in the quantitation of metabolites also observed in the crowded 1H spectrum. Copyright © 1992 Wiley‐Liss, Inc., A Wiley Company

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页码：204 / 210

页数：7

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