CATHESTATINS, NEW CYSTEINE PROTEASE INHIBITORS PRODUCED BY PENICILLIUM-CITRINUM

被引：24

作者：

WOO, JT ^{[1
]}

ONO, H ^{[1
]}

TSUJI, T ^{[1
]}

机构：

[1] SAGAMI CHEM RES CTR, SAGAMIHARA, KANAGAWA 229, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1995年 / 59卷 / 02期

关键词：

D O I：

10.1271/bbb.59.350

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New cysteine protease inhibitors, named cathestatin A and B, have been discovered as metabolites of Penicillium citrinum. Cathestatins were found to be decarbamidoyl analogs of estatins and showed a specific inhibition for cysteine proteases, Cathestatins suppressed parathyroid hormone (PTH)-stimulated Ca-45 release in organ cultures of chick embryonic calvaria.

引用

页码：350 / 352

页数：3

共 6 条

[1]

BARRETT A, 1985, METHOD ENZYMOL, V80, P535

[2] INVIVO AND INVITRO EVIDENCE FOR THE INVOLVEMENT OF CYSTEINE PROTEINASES IN BONE-RESORPTION [J].