SENSITIVITY AND SPECIFICITY-LIKE MEASURES OF THE VALIDITY OF A DIAGNOSTIC-TEST THAT ARE CORRECTED FOR CHANCE AGREEMENT

被引:19
作者
COUGHLIN, SS
PICKLE, LW
机构
[1] Department of Medicine, Divisions of Medical Oncology and Cardiology, Georgetown University School of Medicine, Washington, DC
[2] Vincent T. Lombardi Cancer Research Center, Georgetown University Medical Center, Washington, DC
[3] Office of Research Methodology, National Center For Health Statistics, Hyattsville, MD
关键词
BIOMETRICS; EPIDEMIOLOGIC METHODS; KAPPA; SCREENING; SENSITIVITY; SPECIFICITY; VALIDITY;
D O I
10.1097/00001648-199203000-00017
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Chance agreement may account for a sizeable proportion of the specificity of a screening test when the disease prevalence is low. Conversely, the observed sensitivity may be largely accounted for by chance agreement when the prevalence of disease is high. We derive descriptive statistics that are analogous to sensitivity and specificity and corrected for the agreement expected by chance. These coefficients of validity are shown to be dependent on the true prevalence of disease, as well as sensitivity and specificity.
引用
收藏
页码:178 / 181
页数:4
相关论文
共 7 条
[1]  
Fleiss J.L., Statistical Methods for Rates and Proportions, (1981)
[2]  
Thompson W.D., Walter S.D., A reappraisal of the Kappa coefficient, J Clin Epidemiol, 41, pp. 949-958, (1988)
[3]  
Maclure M., Willett W.C., Misinterpretation and misuse of the Kappa statistic, Am J Epidemiol, 126, pp. 161-169, (1987)
[4]  
Block D.A., Kraemer HC. 2x2 Kappa coefficients: Measures of agreement or association, Biometrics, 45, pp. 269-287, (1989)
[5]  
Sackett D.L., Haynes R.B., Tugwell P., Clinical Epidemiology: A Basic Science for Clinical Medicine, (1985)
[6]  
Spitznagel E.L., Helzer J.E., A proposed solution to the base rate problem in the Kappa statistic, Arch Gen Psychiatry, 42, pp. 725-728, (1985)
[7]  
Youden W.J., Index for rating diagnostic tests, Cancer, 3, pp. 32-35, (1950)