SUCCESSFUL TREATMENT OF REFRACTORY GESTATIONAL TROPHOBLASTIC NEOPLASM WITH HIGH-DOSE ETOPOSIDE AND CYCLOPHOSPHAMIDE

被引：13

作者：

COLLINS, RH ^{[1
]}

WHITE, CS ^{[1
]}

STRINGER, CA ^{[1
]}

FAY, JW ^{[1
]}

机构：

[1] MED CITY HOSP,DEPT ONCOL,DALLAS,TX 75230

来源：

GYNECOLOGIC ONCOLOGY | 1991年 / 43卷 / 03期

关键词：

D O I：

10.1016/0090-8258(91)90044-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A patient with gestational trophoblastic neoplasm failed treatment with several standard chemotherapy regimens and had progressive disease with development of lung and brain metastases and a rising HCG level. Following resection of the metastases and whole-brain radiotherapy she was treated with high-dose etoposide and cyclophosphamide. She promptly attained a complete remission and remains free of disease 15 months after completion of therapy. This regimen, although initially developed for leukemia and lymphoma treatment, has potential as a therapy for refractory gestational trophoblastic neoplasm because it delivers high doses of agents very active in this disease. © 1991.

引用

页码：317 / 319

页数：3

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