INTRAVESICAL ELECTRICAL-STIMULATION - AN EXPERIMENTAL-ANALYSIS OF THE MECHANISM OF ACTION

被引：59

作者：

EBNER, A ^{[1
]}

JIANG, C ^{[1
]}

LINDSTROM, S ^{[1
]}

机构：

[1] GOTHENBURG UNIV,DEPT PHYSIOL,S-41124 GOTHENBURG,SWEDEN

来源：

JOURNAL OF UROLOGY | 1992年 / 148卷 / 03期

关键词：

BLADDER; ELECTRIC STIMULATION THERAPY;

D O I：

10.1016/S0022-5347(17)36778-2

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The working mechanism of intravesical electrical stimulation (IVES) was evaluated in alpha-chloralose anaesthetized cats and rats. IVES involved a direct activation of bladder mechanoreceptor afferents of the A-delta type and as a consequence a central reflex activation of the detrusor. The detrusor response was abolished by bilateral transection of the S1-S3 dorsal roots and by intravesical instillation of lidocaine. The optimal stimulation frequency was 20 Hz. The results offer a theoretical rationale for the use of IVES as treatment of weak detrusor contractility in man.

引用

页码：920 / 924

页数：5

共 16 条

[1] The relation of the hind-brain to micturition. [J].