A NEW VINYLIC ORGANOLITHIUM REAGENT - AN EXPEDIENT C-10+C-10 SYNTHESIS OF RETINAL

被引：12

作者：

DUHAMEL, L ^{[1
]}

DUHAMEL, P ^{[1
]}

LEGALLIC, Y ^{[1
]}

机构：

[1] IRCOF,F-76134 MONT ST AIGNAN,FRANCE

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 02期

关键词：

D O I：

10.1016/S0040-4039(00)60577-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,6-Dimethyl-8-methoxy-1-lithio-octatetra-1,3,5,7-ene 4 is prepared by bromine-lithium exchange from its readily accessible bromo precursor 8. The lithio reagent 4 reacts with carbonyl compounds to give in one pot, after a mild acidic hydrolysis, the retinoid aldehydes 2.

引用

页码：319 / 322

页数：4

共 27 条

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[2]

ANCEL JE, 1989, TETRAHEDRON LETT, V30, P7377

[3]

BESTMANN HJ, 1984, LIEBIGS ANN CHEM, P1740

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