TEA CONSUMPTION AND LUNG-CANCER RISK - A CASE-CONTROL STUDY IN OKINAWA, JAPAN

被引:70
作者
OHNO, Y
WAKAI, K
GENKA, K
OHMINE, K
KAWAMURA, T
TAMAKOSHI, A
AOKI, R
SENDA, M
HAYASHI, Y
NAGAO, K
FUKUMA, S
AOKI, K
机构
[1] NATL OKINAWA HOSP, GINOWAN, OKINAWA 90122, JAPAN
[2] OKINAWA PREFECTURE MENTAL HLTH CARE CTR, HAEBARU, OKINAWA 90111, JAPAN
[3] CHIBA UNIV, SCH MED, INST PULM CANC RES, DIV PATHOL, CHUOH KU, CHIBA 260, JAPAN
[4] CHIBA UNIV, HLTH SCI CTR, INAGE KU, CHIBA 260, JAPAN
[5] CHIBA CANC CTR, CHUOH KU, CHIBA 260, JAPAN
[6] AICHI CANC CTR, CHIKUSA KU, NAGOYA, AICHI 464, JAPAN
来源
JAPANESE JOURNAL OF CANCER RESEARCH | 1995年 / 86卷 / 11期
关键词
TEA; LUNG CANCER; PROTECTIVE EFFECT; CASE-CONTROL STUDY; OKINAWA;
D O I
10.1111/j.1349-7006.1995.tb03016.x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
To disclose the relationship between tea consumption and lung cancer risk, we analyzed the data from a case-control study conducted in Okinawa, Japan from 1988 to 1991. The analysis, based on 333 cases and 666 age-, sex- and residence-matched controls, provided the following major findings. (a) The greater the intake of Okinawan tea (a partially fermented tea), the smaller the risk, particularly in women. For females, the odds ratios (and 95% confidence intervals) for those who consumed 1-4, 5-9, and 10 cups or more of Okinawan tea every day, relative to non-daily tea drinkers, were 0.77 (0.28-2.13), 0.77 (0.26-2.25) and 0.38 (0.12-1.18), respectively (trend: P = 0.032). The corresponding odds ratios for males were 0.85 (0.46-1.55), 0.85 (0.46-1.56) and 0.57 (0.31-1.06) (trend: P = 0.053). (b) The risk reduction by Okinawan tea consumption was detected mainly in squamous cell carcinoma. Daily tea consumption significantly decreased the risk of squamous cell carcinoma in males and females, the odds ratios being 0.50 (95% confidence interval 0.27-0.93) and 0.08 (0.01-0.68), respectively. These findings suggest a protective effect of tea consumption against lung cancer in humans.
引用
收藏
页码:1027 / 1034
页数:8
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