CONFORMATIONAL PROPERTIES OF 3'-AZIDO-3'DEOXYTHYMIDINE (AZT), AN INHIBITOR OF HIV REVERSE-TRANSCRIPTASE

被引：20

作者：

HERZYK, P ^{[1
]}

BEVERIDGE, A ^{[1
]}

NEIDLE, S ^{[1
]}

机构：

[1] INST CANC RES,CANC RES CAMPAIGN BIOMOLEC STRUCT UNIT,SUTTON SM2 5PX,SURREY,ENGLAND

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1987年 / 145卷 / 03期

关键词：

D O I：

10.1016/0006-291X(87)91587-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1356 / 1361

页数：6

共 17 条

[1] CHEMOTHERAPEUTIC APPROACHES TO THE TREATMENT OF THE ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME (AIDS)
DECLERCQ, E
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (09) : 1561 - 1569
[2] THE DEVELOPMENT AND USE OF QUANTUM-MECHANICAL MOLECULAR-MODELS .76. AM1 - A NEW GENERAL-PURPOSE QUANTUM-MECHANICAL MOLECULAR-MODEL
DEWAR, MJS
ZOEBISCH, EG
HEALY, EF
STEWART, JJP
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (13) : 3902 - 3909
[3] PHOSPHORYLATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND SELECTIVE INTERACTION OF THE 5'-TRIPHOSPHATE WITH HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE
FURMAN, PA
FYFE, JA
STCLAIR, MH
WEINHOLD, K
RIDEOUT, JL
FREEMAN, GA
LEHRMAN, SN
BOLOGNESI, DP
BRODER, S
MITSUYA, H
BARRY, DW
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) : 8333 - 8337
[4] FREQUENT DETECTION AND ISOLATION OF CYTOPATHIC RETROVIRUSES (HTLV-III) FROM PATIENTS WITH AIDS AND AT RISK FOR AIDS
GALLO, RC
SALAHUDDIN, SZ
POPOVIC, M
SHEARER, GM
KAPLAN, M
HAYNES, BF
PALKER, TJ
REDFIELD, R
OLESKE, J
SAFAI, B
WHITE, G
FOSTER, P
MARKHAM, PD
[J]. SCIENCE, 1984, 224 (4648) : 500 - 503
[5] HANEEF I, THESIS U LONDON
[6] ELECTRONIC-STRUCTURE OF HYDRAZOIC ACID AND AZIDE ION FROM X-RAY AND ULTRAVIOLET ELECTRON-SPECTROSCOPY
LEE, TH
COLTON, RJ
WHITE, MG
RABALAIS, JW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (17) : 4845 - 4851
[7] SYNTHESIS AND ANTIVIRAL ACTIVITY OF VARIOUS 3'-AZIDO, 3'-AMINO, 2',3'-UNSATURATED, AND 2',3'-DIDEOXY ANALOGS OF PYRIMIDINE DEOXYRIBONUCLEOSIDES AGAINST RETROVIRUSES
LIN, TS
CHEN, MS
MCLAREN, C
GAO, YS
GHAZZOULI, I
PRUSOFF, WH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (02) : 440 - 444
[8] INHIBITION OF THE INVITRO INFECTIVITY AND CYTOPATHIC EFFECT OF HUMAN LYMPHOTROPHIC-T VIRUS "TYPE-III/LYMPHADENOPATHY-ASSOCIATED VIRUS (HTLV-III/LAV) BY 2',3'-DIDEOXYNUCLEOSIDES
MITSUYA, H
BRODER, S
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (06) : 1911 - 1915
[9] 3'-AZIDO-3'-DEOXYTHYMIDINE (BW A509U) - AN ANTIVIRAL AGENT THAT INHIBITS THE INFECTIVITY AND CYTOPATHIC EFFECT OF HUMAN LYMPHOTROPIC-T VIRUS TYPE-III LYMPHADENOPATHY-ASSOCIATED VIRUS INVITRO
MITSUYA, H
WEINHOLD, KJ
FURMAN, PA
STCLAIR, MH
LEHRMAN, SN
GALLO, RC
BOLOGNESI, D
BARRY, DW
BRODER, S
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (20) : 7096 - 7100
[10] CONFORMATIONAL STUDIES OF NUCLEIC-ACIDS .2. THE CONFORMATIONAL ENERGETICS OF COMMONLY OCCURRING NUCLEOSIDES
PEARLMAN, DA
KIM, SH
[J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1985, 3 (01) : 99 - 125

← 1 2 →