CELLULAR AUTOMATON MODEL OF VENTRICULAR-FIBRILLATION

被引：6

作者：

MITCHELL, RH

BAILEY, AH

ANDERSON, J

机构：

[1] Department of Electrical and Electronic Engineering, The University of Ulster

来源：

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING | 1992年 / 39卷 / 03期

关键词：

D O I：

10.1109/10.125010

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A theoretical analysis of ventricular fibrillation and the requirements for fibrillation are performed using a discrete element neighborhood (cellular automaton) model of ventricular conduction. The model is configured as a 2500 element rectangular grid on the surface of a cylinder. It is shown that vulnerability to fibrillation is strongly influenced by excited state duration which primarily determines the nature of the underlying reentry activity. As excited state duration is increased fibrillation changes from "coarse" macroreentrant activity to the more chaotic "fine" fibrillation sustained by multiple wavelets of microreentry. In general, defibrillation is achieved by a stimulus strong enough to depolarize the majority of relative refractory elements. The threshold for defibrillation is increased for the more irregular microreentrant fibrillation.

引用

页码：253 / 259

页数：7

共 12 条

[1]

BAILEY AH, 1988, THESIS U ULSTER

[2]

KRINSKII V. I., 1966, BIOFIZIKA, V11, P676

[3] COMPUTER MODEL OF ATRIAL FIBRILLATION [J].