DELETION 12P IN DENOVO ACUTE MYELOID-LEUKEMIA - AN ASSOCIATION WITH EARLY PROGENITOR-CELL

被引：14

作者：

CHAN, LC ^{[1
]}

KWONG, YL ^{[1
]}

LIU, HW ^{[1
]}

LEE, CP ^{[1
]}

LIE, KW ^{[1
]}

CHAN, AYY ^{[1
]}

机构：

[1] UNIV HONG KONG, QUEEN MARY HOSP, DEPT MED, HONG KONG, HONG KONG

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 62卷 / 01期

关键词：

D O I：

10.1016/0165-4608(92)90037-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Deletion of the short arm of chromosome 12 as the sole karyotypic abnormality was found in three cases of acute myeloblastic leukemia (AML). In contrast to what has previously been reported in the literature, none of our cases had an antecedent history of myelodysplasia or toxic exposure, and basophilia was absent. Two cases were terminal deoxynucleotidyl transferase (TdT) positive, suggesting involvement of an early progenitor cell.

引用

页码：47 / 49

页数：3

共 17 条

[1] PROPOSED REVISED CRITERIA FOR THE CLASSIFICATION OF ACUTE MYELOID-LEUKEMIA - A REPORT OF THE FRENCH-AMERICAN-BRITISH COOPERATIVE GROUP [J].

BENNETT, JM ;

CATOVSKY, D ;

DANIEL, MT ;

FLANDRIN, G ;

GALTON, DAG ;

GRALNICK, HR ;

SULTAN, C .

ANNALS OF INTERNAL MEDICINE, 1985, 103 (04) :620-625

[2] CYTOGENETIC STUDIES OF 44 T-CELL ACUTE LYMPHOBLASTIC LEUKEMIAS [J].

BERGER, R ;

LECONIAT, M ;

VECCHIONE, D ;

DERRE, J ;

CHEN, SJ .

CANCER GENETICS AND CYTOGENETICS, 1990, 44 (01) :69-75

[3] ABNORMALITIES OF THE SHORT ARM OF CHROMOSOME-12 IN ACUTE NONLYMPHOCYTIC LEUKEMIA AND DYSMYELOPOIETIC SYNDROME [J].

BERGER, R ;

BERNHEIM, A ;

LECONIAT, M ;

VECCHIONE, D ;

PACOT, A ;

DANIEL, MT ;

FLANDRIN, G .

CANCER GENETICS AND CYTOGENETICS, 1986, 19 (3-4) :281-289

[4]

CHAN LC, IN PRESS CANCER GENE

[5]

DANIEL MT, 1985, CR ACAD SCI III-VIE, V301, P299

[6]

LOCOCO F, 1989, BRIT J HAEMATOL, V73, P480

[7]

MICHAUX JL, 1986, CANCER GENET CYTOGEN, V21, P11

[8]

MITELMAN F, 1991, CATALOG CHROMOSOME A, P923

[9] TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE POSITIVE ACUTE MYELOID-LEUKEMIA - AN ASSOCIATION WITH IMMATURE MYELOBLASTIC-LEUKEMIA [J].

PARREIRA, A ;

DEOLIVEIRA, MSP ;

MATUTES, E ;

FORONI, L ;

MORILLA, R ;

CATOVSKY, D .

BRITISH JOURNAL OF HAEMATOLOGY, 1988, 69 (02) :219-224

[10]

RAIMONDI SC, 1986, BLOOD, V68, P69

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