THE ORIGIN ISOCHROMOSOMES AND THEIR SIGNIFICANCE IN TUMORIGENESIS OF HUMAN LUNG-CANCER

被引:3
作者
FU, SB [1 ]
LI, P [1 ]
FENG, XL [1 ]
LIU, CX [1 ]
LIU, QZ [1 ]
机构
[1] HARBIN MED COLL,DEPT BIOL,MED GENET LAB,HARBIN,PEOPLES R CHINA
关键词
D O I
10.1016/0165-4608(94)90009-4
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Isochromosomes related to chromosomes 1, 5, 6, 8, and 9 were frequently observed in 23 cases of lung cancer. Their existence in tumor cells might be nonrandom. Premature centromere separation (PCS) was found in the PGT-131 cell line of a lung cancer. It is suggested that PCS may play a role in the formation of isochromosomes in lung cancer.
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页码:120 / 122
页数:3
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