SEVERE LACTIC-ACIDOSIS FOLLOWING THEOPHYLLINE OVERDOSE

被引：13

作者：

BERNARD, S

机构：

[1] Departments of Emergency Medicine and Intensive Care, Dandenong and District Hospital, Dandenong, Vic.

来源：

ANNALS OF EMERGENCY MEDICINE | 1991年 / 20卷 / 10期

关键词：

lactic acidosis; overdose; theophylline;

D O I：

10.1016/S0196-0644(05)81392-7

中图分类号：

R4 [临床医学];

学科分类号：

1002 [临床医学]; 100602 [中西医结合临床];

摘要：

The patient with theophylline overdose commonly presents with gastrointestinal, cardiovascular, neurologic, and electrolyte abnormalities. Respiratory alkalosis is the most common acid-base alteration, but mild metabolic acidosis has been reported. Two cases of severe lactic acidosis (pH 6.67 and 6.63) in patients without hypoxemia, shock, or prolonged seizure activity are reported. Possible causative mechanisms and aspects of therapy are discussed. Theophyline toxicity should be considered when an unconscious patient with concurrent severe metabolic acidosis presents to the emergency department.

引用

页码：1135 / 1137

页数：3

共 19 条

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