THE HEMATOPOIETIC REGULATORS - AN EMBARRASSMENT OF RICHES

被引：16

作者：

METCALF, D

机构：

[1] Walter and Eliza Hall Institute of Medical Research, P.O. Royal Melbourne Hospital, Victoria

来源：

BIOESSAYS | 1992年 / 14卷 / 12期

关键词：

D O I：

10.1002/bies.950141202

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A large, and growing, group of glycoprotein regulators is now recognized to control the proliferation, maturation and functional activity of the eight major families of blood cells. Each hemopoietic regulator is the product of multiple cell types and there is a puzzling redundancy of regulators able to stimulate each subfamily of hemopoietic cells. Each regulator is polyfunctional but it remains unclear how a single type of activated receptor is able to initiate the diverse cellular responses induced.

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页码：799 / 805

页数：7

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