ANTIPLATELET DRUGS

被引：8

作者：

FITZGERALD, GA

MEAGHER, EA

机构：

[1] Centre for Cardiovascular Science, Department of Medicine and Experimental Therapeutics, University College, Dublin

来源：

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 1994年 / 24卷

基金：

英国惠康基金;

关键词：

ANTIPLATELET COMPOUNDS; ASPIRIN; DIPYRIDAMOLE; TICLOPIDINE; GPIIB/IIIA;

D O I：

10.1111/j.1365-2362.1994.tb02427.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The evidence in support of the safety and efficacy of aspirin in the secondary prevention of platelet dependent vascular-occlusion is compelling. The utility of this drug has stalled the development of potential competitors, such as thromboxane antagonists. The emergence of glycoprotein IIb/IIIa antagonists as the most promising competitors for aspirin has focused attention on the possibility of delivering these drugs at an effective dose safely.

引用

页码：46 / 49

页数：4

共 41 条

[1]

AMBROSE JA, 1986, J AM COLL CARDIOL, V7, P474

[2]

[Anonymous], 1988, LANCET, V2, P349

[3]

[Anonymous], 1988, BRIT MED J, V296, P320

[4] ANTIPLATELET TREATMENT WITH TICLOPIDINE IN UNSTABLE ANGINA - A CONTROLLED MULTICENTER CLINICAL-TRIAL [J].

BALSANO, F ;

RIZZON, P ;

VIOLI, F ;

SCRUTINIO, D ;

CIMMINIELLO, C ;

AGUGLIA, F ;

PASOTTI, C ;

RUDELLI, G .

CIRCULATION, 1990, 82 (01) :17-26

[5] EFFECT OF LOW-DOSE ASPIRIN ON FETAL AND MATERNAL GENERATION OF THROMBOXANE BY PLATELETS IN WOMEN AT RISK FOR PREGNANCY-INDUCED HYPERTENSION [J].

BENIGNI, A ;

GREGORINI, G ;

FRUSCA, T ;

CHIABRANDO, C ;

BALLERINI, S ;

VALCAMONICO, A ;

ORISIO, S ;

PICCINELLI, A ;

PINCIROLI, V ;

FANELLI, R ;

GASTALDI, A ;

REMUZZI, G .

NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (06) :357-362

[6] SUPPRESSION OF EICOSANOID BIOSYNTHESIS DURING CORONARY ANGIOPLASTY BY FISH OIL AND ASPIRIN [J].

BRADEN, GA ;

KNAPP, HR ;

FITZGERALD, GA .

CIRCULATION, 1991, 84 (02) :679-685

[7]

CHARMAN W, 1992, IN PRESS BR J CLIN P

[8]

Charman W. N., 1992, P74

[9] SUPPRESSION OF THROMBOXANE-A2 BUT NOT OF SYSTEMIC PROSTACYCLIN BY CONTROLLED-RELEASE ASPIRIN [J].

CLARKE, RJ ;

MAYO, G ;

PRICE, P ;

FITZGERALD, GA .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (16) :1137-1141

[10]

DAVIES M J, 1989, P181

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