NEW N-ALKYL DERIVATIVES OF AMPHOTERICIN-B - SYNTHESIS AND BIOLOGICAL PROPERTIES

被引：20

作者：

CZERWINSKI, A ^{[1
]}

KONIG, WA ^{[1
]}

ZIENIAWA, T ^{[1
]}

SOWINSKI, P ^{[1
]}

SINNWELL, V ^{[1
]}

MILEWSKI, S ^{[1
]}

BOROWSKI, E ^{[1
]}

机构：

[1] UNIV HAMBURG,INST ORGAN CHEM,W-2000 HAMBURG 13,GERMANY

来源：

JOURNAL OF ANTIBIOTICS | 1991年 / 44卷 / 09期

关键词：

D O I：

10.7164/antibiotics.44.979

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The synthesis of new N-alkyl amphotericin B derivatives obtained in the Michael addition reaction of the antibiotic with N-substituted maleimides is described and in vitro biological data are presented.

引用

页码：979 / 984

页数：6

共 15 条

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