ENDOGENOUS ESTRADIOL AND PROGESTERONE CONCENTRATIONS IN SMOKERS ON ORAL-CONTRACEPTIVES

被引：14

作者：

BASU, J ^{[1
]}

MIKHAIL, MS ^{[1
]}

PALAN, PR ^{[1
]}

THYSEN, B ^{[1
]}

BLOCH, E ^{[1
]}

ROMNEY, SL ^{[1
]}

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT GYNECOL,BRONX,NY 10461

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 1992年 / 33卷 / 04期

关键词：

CIGARETTE SMOKING; PREMENOPAUSAL WOMEN; 17-BETA-ESTRADIOL; RADIOIMMUNOASSAY; SERUM HORMONE LEVELS;

D O I：

10.1159/000294888

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The simultaneous effects of cigarette smoking and oral contraceptives on serum estradiol and progesterone levels were investigated in 114 premenopausal women. Serum 17-beta-estradiol and progesterone levels were measured by radioimmunoassay. In smokers, estradiol and progesterone levels were significantly lower (p < 0.025). In smokers using oral contraceptives, estradiol and progesterone levels were the lowest (p < 0.001 and p < 0.01, respectively). The findings suggest that smoking and oral contraceptives independently lower serum estradiol and progesterone concentrations in premenopausal women and that the effects may be additive.

引用

页码：224 / 227

页数：4

共 20 条

[1] CIGARETTE-SMOKING AND THE AGE AT MENOPAUSE [J].

ADENA, MA ;

GALLAGHER, HG .

ANNALS OF HUMAN BIOLOGY, 1982, 9 (02) :121-130

[2]

BARBIERI RL, 1986, FERTIL STERIL, V46, P232

[3] CIGARETTE-SMOKING IN PREGNANCY RESULTS IN MARKED DECREASE IN MATERNAL HCG AND ESTRADIOL LEVELS [J].

BERNSTEIN, L ;

PIKE, MC ;

LOBO, RA ;

DEPUE, RH ;

ROSS, RK ;

HENDERSON, BE .

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1989, 96 (01) :92-96

[4] THE EFFECT OF SMOKING IN PREGNANCY ON MATERNAL SERUM ALPHA-FETOPROTEIN, UNCONJUGATED ESTRIOL, HUMAN CHORIONIC-GONADOTROPIN, PROGESTERONE AND DEHYDROEPIANDROSTERONE SULFATE LEVELS [J].

CUCKLE, HS ;

WALD, NJ ;

DENSEM, JW ;

ROYSTON, P ;

KNIGHT, GJ ;

HADDOW, JE ;

PALOMAKI, GE ;

CANICK, JA .

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1990, 97 (03) :272-274

[5]

DAFAU M, 1970, LANCET, V1, P271

[6] OSTEOPOROSIS OF SLENDER SMOKER - VERTEBRAL COMPRESSION FRACTURES AND LOSS OF METACARPAL CORTEX IN RELATION TO POSTMENOPAUSAL CIGARETTE-SMOKING AND LACK OF OBESITY [J].

DANIELL, HW .

ARCHIVES OF INTERNAL MEDICINE, 1976, 136 (03) :298-304

[7]

ESSENBERG J M, 1951, West J Surg Obstet Gynecol, V59, P27

[8] CIGARETTE-SMOKING AND AGE AT NATURAL MENOPAUSE [J].

KAUFMAN, DW ;

SLONE, D ;

ROSENBERG, L ;

MIETTINEN, OS ;

SHAPIRO, S .

AMERICAN JOURNAL OF PUBLIC HEALTH, 1980, 70 (04) :420-422

[9] CROSS-REACTION OF CONTRACEPTIVE STEROIDS IN COMPETITIVE BINDING ASSAYS OF PROGESTERONE AND ESTRADIOL [J].

KHARMA, K ;

THORNEYCROFT, IH ;

STONE, S ;

NAKAMURA, RM ;

MISHELL, DR .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1972, 112 (05) :676-+

[10]

LINDSAY R, 1981, OSTEOPOROSIS RECENT, P481

← 1 2 →