ENTHALPY OF HELIX-COIL TRANSITION OF DNA - DEPENDENCE ON NA+ CONCENTRATION AND GC-CONTENT

被引：10

作者：

KARAPETIAN, AT

VARDEVANIAN, PO

FRANKKAMENETSKII, MD

机构：

[1] ACAD SCI USSR,INST MOLEC GENET,KURCHATOV SQ,MOSCOW 123182,USSR

[2] KIROVAKAN TEACHERS TRAINING INST,KIROVAKAN,ARMENIA,USSR

[3] YEREVAN STATE UNIV,EREVAN 375049,ARMENIA,USSR

来源：

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS | 1990年 / 8卷 / 01期

关键词：

D O I：

10.1080/07391102.1990.10507794

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The enthalpy of helix-coil transition of DNA (AH) is determined from the experiments on DNA melting with ligands by means of absolutely general formula, which contains only values directly known from the experiment (M.D. Frank-Kamenetskii, and A.T. Karapetian, Mol. Biol. USSR 6,621 (1972)) with the combination of the “area” method (P.O. Vardevanian, et al, Biophysica 28, 130 (1983)). The experimentally obtained data show that AH depends on both concentration of Na+ in solution and GC-content of DNA and is of high accuracy. © Taylor & Francis Group, LLC.

引用

页码：131 / 138

页数：8

共 23 条

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[2]

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[3]

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[4]

FRANKKAM.MD, 1972, MOLEK BIOL, V6, P621