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ENVIRONMENTAL-REGULATION OF BACTERIAL VIRULENCE - IMPLICATIONS FOR VACCINE DESIGN AND PRODUCTION

被引：24
作者：
GRIFFITHS, E
机构：
[1] E. Griffithus is at the National Institute for Biological Standards and Control, Potters Bar, Herts. EN6 3QG, Blanche Lane, South Mimms
来源：
TRENDS IN BIOTECHNOLOGY | 1991年 / 9卷 / 09期
关键词：
D O I：
10.1016/0167-7799(91)90101-M
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
There is now overwhelming evidence that many of the crucial virulence determinants of pathogenic bacteria are environmentally regulated and expressed only under certain conditions. Much progress is currently being made in identifying these factors and in understanding the molecular mechanisms controlling their production. This information is crucial for the understanding of microbial pathogenicity and it has important practical implications for vaccine design and production.
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页码：309 / 315
页数：7
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