SYNTHESIS AND CHARACTERIZATION OF ALKYL-SUBSTITUTED, ALKENYL-SUBSTITUTED, ACYL-SUBSTITUTED AND NITROGEN-SUBSTITUTED DERIVATIVES OF THE POTENT PHOTOTOXIN ALPHA-TERTHIOPHENE

被引:31
作者
SOUCYBREAU, C [1 ]
MACEACHERN, A [1 ]
LEITCH, LC [1 ]
ARNASON, T [1 ]
MORAND, P [1 ]
机构
[1] UNIV OTTAWA, OTTAWA CARLETON INST BIOL, OTTAWA K1N 6N5, ONTARIO, CANADA
关键词
D O I
10.1002/jhet.5570280239
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Some alkyl-, alkenyl-, acyl- and nitrogen- derivatives of alpha-terthienyl 1 have been synthesized in an effort to expand the potential insecticidal activity profile of this compound. The introduction of substituents was carried out directly on the alpha-terthienyl molecule. Three compounds were isolated in the nitration reaction and the compounds have been identified as 5-nitro-2,2':5',2''-terthiophene 5, 3'-nitro-2,2':5',2''-terthiophene 6 and 3-nitro-2,2':5',2''-terthiophene 7 respectively. Preliminary results of biological activity are reported.
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收藏
页码:411 / 416
页数:6
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