SYNTHESIS OF MODIFIED PEPTIDES INCORPORATING AN N-TERMINAL OR C-TERMINAL PHOSPHONATE MOIETY

被引：21

作者：

COUTROT, P

GRISON, C

CHARBONNIERGERARDIN, C

机构：

来源：

TETRAHEDRON | 1992年 / 48卷 / 45期

关键词：

D O I：

10.1016/S0040-4020(01)92278-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general route to phosphopeptids with a 2-oxoalkylphosphonate moiety at the terminal N-aminogroup or with a 1-aminoalkylphosphonate moiety at the terminal C-carboxyl group is described. The method allows the preparation of various phosphopeptids with an alpha-alkylated carbon atom on the P-C bond from the very available dialkylphosphonoalcanoic acids as starting products.

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页码：9841 / 9868

页数：28

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