MUSCARINIC CHOLINERGIC RECEPTORS IN THE RAT DEEP CEREBELLAR NUCLEI - A QUANTITATIVE AUTORADIOGRAPHIC STUDY

被引：9

作者：

BEITZ, AJ ^{[1
]}

BUGGY, J ^{[1
]}

FLETCHER, TF ^{[1
]}

WEINER, L ^{[1
]}

机构：

[1] UNIV S CAROLINA, DEPT PHYSIOL, COLUMBIA, SC 29208 USA

来源：

NEUROSCIENCE LETTERS | 1984年 / 50卷 / 1-3期

关键词：

D O I：

10.1016/0304-3940(84)90470-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The distribution of muscarinic cholinergic receptors within the rat deep cerebellar nuclei was analyzed using in vitro receptor binding of [3H]quinuclidinylbenzilate (QNB) in conjunction with autoradiography. The highest density of QNB binding sites occurred in the lateral cerebellar (dentate) nucleus. Interpositus nuclei displayed an intermediate density of muscarinic cholinergic binding sites with the posterior interpositus nucleus demonstrating higher binding than the anterior nucleus. The fastigial (medial) cerebellar nucleus exhibited the lowest levels of QNB binding among the 4 cerebellar nuclei. Evidently, musarcinic cholinergic receptors are present in the deep cerebellar nuclei and differences in receptor density occur among the 4 nuclear groups.

引用

页码：103 / 109

页数：7

共 28 条

[1] QUANTITATIVE MEASUREMENT OF LOCAL CEREBRAL METABOLIC-RATE FOR GLUCOSE UTILIZING TRITIATED 2-DEOXYGLUCOSE [J].