SULFONYL DERIVATIVES OF BENZOTRIAZOLE .1. A NOVEL-APPROACH TO THE ACTIVATION OF CARBOXYLIC-ACIDS

被引：65

作者：

KATRITZKY, AR

SHOBANA, N

PERNAK, J

AFRIDI, AS

FAN, WQ

机构：

[1] Center For Heterocyclic Compounds, Department of Chemistry University of Florida, Gainesville

来源：

TETRAHEDRON | 1992年 / 48卷 / 37期

关键词：

D O I：

10.1016/S0040-4020(01)80459-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Acylbenzotriazoles (8,R=Me,Et,n-Bu and Ph) are prepared in good yields by fusion of benzotriazole and acid chlorides at 80 - 100-degrees-C. In cases when the corresponding acid chlorides are not available, 1-acylbenzotriazoles are conveniently available from 1-(1-methanesulfonyl)benzotriazole and the respective carboxylic acids as illustrated by the preparation of 2-, 3-, and 4-pyridoyl-, 2-pyrrolylcarbonyl- and 2-furoyl-benzotriazole in yields of 80 - 95%. Preparations of two sulfonyl derivatives of benzotriazole are also described.

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页码：7817 / 7822

页数：6

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