EVIDENCE FOR PULSATILE SECRETION OF HUMAN ATRIAL-NATRIURETIC-PEPTIDE IN HEALTHY-SUBJECTS

被引：1

作者：

HAAK, T ^{[1
]}

JUNGMANN, E ^{[1
]}

SCHOFFLING, K ^{[1
]}

USADEL, KH ^{[1
]}

机构：

[1] UNIV FRANKFURT,CTR INTERNAL MED,DEPT ENDOCRINOL,W-6000 FRANKFURT,GERMANY

来源：

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY | 1992年 / 99卷 / 02期

关键词：

HUMAN ATRIAL NATRIURETIC PEPTIDE (HANP); PULSATILE SECRETION PATTERN;

D O I：

10.1055/s-0029-1211147

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The secretion pattern of human atrial natriuretic peptide (hANP) was investigated in 8 healthy male volunteers. Blood was drawn in 2 minute intervals for 90 minutes and in a second study in 4 minute intervals for 180 minutes. Base-line hANP plasma levels varied in a pulsatile secretion pattern of regular pulses every 9 +/- 1 minutes. Additionally long-term oscillations of 34 +/- 4 minutes were found. These data suggest that under basal conditions hANP varies in a pulsatile fashion.

引用

页码：108 / 109

页数：2

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