LONG TELOMERES IN THE POLYTENE CHROMOSOMES OF DROSOPHILA-MELANOGASTER ARE ASSOCIATED WITH AMPLIFICATION OF SUBTELOMERIC REPEAT SEQUENCES

被引：7

作者：

DANILEVSKAYA, ON ^{[1
]}

LAPTA, GE ^{[1
]}

机构：

[1] AM GORKII STATE UNIV,KHARKOV,UKRAINE,USSR

来源：

GENETICS SELECTION EVOLUTION | 1991年 / 23卷 / 01期

关键词：

DROSOPHILA-MELANOGASTER; POLYTENE CHROMOSOME; TELOMERE LENGTH; REPEAT SEQUENCE; AMPLIFICATION;

D O I：

10.1051/gse:19910102

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The T-32 strain of Drosophila melanogaster, which was originally selected for heat resistance, is characterized by having exceptionally long tips in chromosomes X and 2L in the polytene salivary gland chromosomes. Six sublines differing in telomere length in different chromosomes were selected at an elevated temperature (32-degrees-C). The morphological characteristics of the telomeres in each subline are stable for a number of generations at 23-degrees-C. The additional chromatin in the long telomeres effectively hybridizes with a DNA sequence designated Dm665, which is related to the He-T family of heterochromatin- and telomere-associated sequences. The short telomeres show weak or no hybridization with the Dm665 fragment. This result implies that at least part of the morphological changes in telomere length in polytene chromosomes results from different degrees of amplification of the telomere-associated sequences.

引用

页码：15 / 24

页数：10

共 13 条

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