CORRELATION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE NEUROTOXICITY WITH BLOOD-BRAIN-BARRIER MONOAMINE-OXIDASE ACTIVITY

被引：80

作者：

KALARIA, RN

MITCHELL, MJ

HARIK, SI

机构：

[1] UNIV HOSP CLEVELAND,DAVID S INGALLS SR NEUROL INST,DEPT NEUROL,CLEVELAND,OH 44106

[2] CASE WESTERN RESERVE UNIV,SCH MED,DEPT NEUROL,CLEVELAND,OH 44106

[3] CASE WESTERN RESERVE UNIV,SCH MED,DEPT PHARMACOL,CLEVELAND,OH 44106

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1987年 / 84卷 / 10期

关键词：

D O I：

10.1073/pnas.84.10.3521

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：3521 / 3525

页数：5

共 35 条

[1] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE [J].

BURNS, RS ;

CHIUEH, CC ;

MARKEY, SP ;

EBERT, MH ;

JACOBOWITZ, DM ;

KOPIN, IJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14) :4546-4550

[2] DIFFERENCES IN THE STRUCTURE OF A AND B-FORMS OF HUMAN MONOAMINE-OXIDASE [J].

CAWTHON, RM ;

PINTAR, JE ;

HASELTINE, FP ;

BREAKEFIELD, XO .

JOURNAL OF NEUROCHEMISTRY, 1981, 37 (02) :363-372

[3] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE [J].

CHIBA, K ;

TREVOR, A ;

CASTAGNOLI, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) :574-578

[4]

CHIBA K, 1985, DRUG METAB DISPOS, V13, P342

[5] CHRONIC PARKINSONISM SECONDARY TO INTRAVENOUS-INJECTION OF MEPERIDINE ANALOGS [J].

DAVIS, GC ;

WILLIAMS, AC ;

MARKEY, SP ;

EBERT, MH ;

CAINE, ED ;

REICHERT, CM ;

KOPIN, IJ .

PSYCHIATRY RESEARCH, 1979, 1 (03) :249-254

[6] IDENTIFICATION AND CHARACTERIZATION OF THE GLUCOSE TRANSPORTER OF THE BLOOD-BRAIN-BARRIER BY CYTOCHALASIN-B BINDING AND IMMUNOLOGICAL REACTIVITY [J].

DICK, APK ;

HARIK, SI ;

KLIP, A ;

WALKER, DM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (22) :7233-7237

[7] MONOAMINE OXIDASE-A AND OXIDASE-B ARE DIFFERENTIALLY REGULATED BY GLUCOCORTICOIDS AND AGING IN HUMAN-SKIN FIBROBLASTS [J].

EDELSTEIN, SB ;

BREAKEFIELD, XO .

CELLULAR AND MOLECULAR NEUROBIOLOGY, 1986, 6 (02) :121-150

[8] GOLDEN-HAMSTER PANCREATIC-ISLETS - A TISSUE RICH IN MONOAMINE-OXIDASE [J].

FELDMAN, JM ;

WHITEOWEN, C ;

KLATT, C .

ENDOCRINOLOGY, 1980, 107 (05) :1504-1511

[9] BARRIER MECHANISMS FOR NEUROTRANSMITTER MONOAMINES AND THEIR PRECURSORS AT THE BLOOD-BRAIN INTERFACE [J].

HARDEBO, JE ;

OWMAN, C .

ANNALS OF NEUROLOGY, 1980, 8 (01) :1-11

[10] ADRENERGIC AND CHOLINERGIC RECEPTORS OF CEREBRAL MICRO-VESSELS [J].

HARIK, SI ;

SHARMA, VK ;

WETHERBEE, JR ;

WARREN, RH ;

BANERJEE, SP .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1981, 1 (03) :329-338

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