A CYTOTOXIC DIACETYLENE FROM DENDROPANAX-ARBOREUS

被引：28

作者：

SETZER, WN

GREEN, TJ

WHITAKER, KW

MORIARITY, DM

YANCEY, CA

LAWTON, RO

BATES, RB

机构：

[1] UNIV ALABAMA,DEPT BIOL SCI,HUNTSVILLE,AL 35899

[2] UNIV ARIZONA,DEPT CHEM,TUCSON,AZ 85721

来源：

PLANTA MEDICA | 1995年 / 61卷 / 05期

关键词：

D O I：

10.1055/s-2006-958139

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The crude ethanol extract from the leaves of Dendropanax arboreus (Araliaceae) from Monteverde, Costa Rica, exhibits cytotoxic activity against Hep-G2, A-431, H-4IIE, and L-1210 tumor cell lines, but is not toxic against normal hepatocytes. The active component has been isolated by activity-directed separation and identified by H-1- and C-13-NMR spectroscopy as the acetylenic compound cis-1,9,16-heptadecatriene-4, 6-deyne-3,8-diol.

引用

页码：470 / 471

页数：2

共 12 条

[1] NATURAL-PRODUCTS FROM VIETNAMESE PLANTS .6. 3-ALPHA-HYDROXY-LUP-20(29)-ENE-23,28-DIOIC ACID FROM SCHEFFLERA-OCTOPHYLLA [J].