KINETICS OF A MULTISTATE ENZYME IN A LARGE OSCILLATING FIELD

被引：47

作者：

ROBERTSON, B

ASTUMIAN, RD

机构：

[1] Chemical Process Metrology Division, National Institute of Standards and Technology, Gaithersburg, Maryland

来源：

BIOPHYSICAL JOURNAL | 1990年 / 57卷 / 04期

关键词：

D O I：

10.1016/S0006-3495(90)82590-X

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A simple, general, and efficient method for calculating the response of a set of coupled first-order (or pseudo-first-order) chemical reactions to an arbitrarily large periodic field is described. The method is applied to a four-state membrane transport enzyme that is electroconformationally coupled to an ac field, i.e., the enzyme has electric charges that move concomitantly with a conformational transition. The calculation is done both for enzymes in a planar membrane and for enzymes in the spherical membrane of a cell or vesicle in suspension. © 1990, The Biophysical Society. All rights reserved.

引用

页码：689 / 696

页数：8

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