SELECTIVE MONOFLUORINATION AND DIFLUORINATION OF ENOLATES

被引：74

作者：

DIFFERDING, E

RUEGG, GM

LANG, RW

机构：

[1] Central Research Laboratories, Ciba-Geigy AG

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 15期

关键词：

D O I：

10.1016/S0040-4039(00)74328-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The selective transformation of enolates into mono- and difluorinated carbonyl compounds can be performed in a one-pot procedure using N-F-sultam 1. The yields and the selectivity of the fluorination strongly depend on the counterion of the enolate and the acidity of the protons alpha to the carbonyl group.

引用

页码：1779 / 1782

页数：4

共 16 条

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