BINDING OF METRONIDAZOLE AND ITS DERIVATIVES TO PLASMA-PROTEINS - ASSESSMENT OF DRUG BINDING PHENOMENON

被引：33

作者：

SANVORDEKER, DR ^{[1
]}

CHIEN, YW ^{[1
]}

LIN, TK ^{[1
]}

LAMBERT, HJ ^{[1
]}

机构：

[1] GD SEARLE & CO,SEARLE LABS,PROD DEV DEPT,BIOPHARM GRP,SKOKIE,IL 60076

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1975年 / 64卷 / 11期

关键词：

D O I：

10.1002/jps.2600641111

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1797 / 1803

页数：7

共 28 条

[1] GROUND STATES OF SIGMA-BONDED MOLECULES .10.EXTENSION OF MINDO/2 METHOD TO COMPOUNDS CONTAINING NITROGEN AND/OR OXYGEN [J].

BODOR, N ;

DEWAR, MJS ;

HARGET, A ;

HASELBACH, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (13) :3854-+

[2] DISPLACEMENT OF 1 DRUG BY ANOTHER FROM CARRIER OR RECEPTOR SITES [J].

BRODIE, BB .

PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE-LONDON, 1965, 58 (11P2) :946-+

[3] COMPARATIVE BINDING OF DISOPYRAMIDE PHOSPHATE AND QUINIDINE SULFATE TO HUMAN PLASMA-PROTEINS [J].

CHIEN, YW ;

LAMBERT, HJ ;

KARIM, A .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1974, 63 (12) :1877-1879

[4]

CHIEN YW, 1974, ABSTRACTS PAPERS APH, V4, P124

[5]

DETTLI L, 1968, FARMACO-ED SCI, V23, P795

[6] SELECTIVE TOXICITY OF ANTIMICROBIAL NITROHETEROCYCLIC DRUGS [J].

EDWARDS, DI ;

DYE, M ;

CARNE, H .

JOURNAL OF GENERAL MICROBIOLOGY, 1973, 76 (MAY) :135-145

[7] NUCLEAR MAGNETIC RELAXATION STUDY OF INTERMOLECULAR COMPLEXES . MECHANISM OF PENICILLIN BINDING TO SERUM ALBUMIN [J].

FISCHER, JJ ;

JARDETZK.O .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (14) :3237-&

[8]

FUJITA T, 1964, J AM CHEM SOC, V86, P5174

[9] CONCENTRATION OF ETHAMBUTOL IN CEREBROSPINAL-FLUID IN MAN AS A FUNCTION OF NON-PROTEIN-BOUND DRUG FRACTION IN SERUM [J].

GUNDERTREMY, U ;

KLETT, M ;

WEBER, E .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1973, 6 (02) :133-136

[10] USE OF SUBSTITUENT CONSTANTS IN ANALYSIS OF STRUCTURE-ACTIVITY RELATIONSHIP IN PENICILLIN DERIVATIVES [J].

HANSCH, C ;

STEWARD, AR .

JOURNAL OF MEDICINAL CHEMISTRY, 1964, 7 (06) :691-&

← 1 2 3 →