HETEROGENEITY IN THE SPECIFIC ACTIVITY AND METHOTREXATE SENSITIVITY OF DIHYDROFOLATE-REDUCTASE FROM BLAST CELLS OF ACUTE MYELOGENOUS LEUKEMIA PATIENTS

被引：21

作者：

DEDHAR, S ^{[1
]}

HARTLEY, D ^{[1
]}

FITZGIBBONS, D ^{[1
]}

PHILLIPS, G ^{[1
]}

GOLDIE, JH ^{[1
]}

机构：

[1] CANC CONTROL AGCY BRITISH COLUMBIA,DEPT MED ONCOL,ADV THERAPEUT SECT,VANCOUVER V5Z 3J3,BC,CANADA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 1985年 / 3卷 / 11期

关键词：

D O I：

10.1200/JCO.1985.3.11.1545

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1545 / 1552

页数：8

共 20 条

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[6]

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[7] INHIBITION OF A METHOTREXATE-INSENSITIVE DIHYDROFOLATE-REDUCTASE FROM L5178Y CELLS BY SUBSTITUTED TRIAZINES AND QUINAZOLINES [J].

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[8] OVERPRODUCTION OF DIHYDROFOLATE-REDUCTASE AND GENE AMPLIFICATION IN METHOTREXATE-RESISTANT CHINESE-HAMSTER OVARY CELLS [J].

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[10] A METHOTREXATE INSENSITIVE VARIANT OF FOLATE REDUCTASE PRESENT IN 2 LINE OF METHOTREXATE-RESISTANT L5178Y CELLS [J].

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