MEASURED DOSE TO OVARIES AND TESTES FROM HODGKIN FIELDS AND DETERMINATION OF GENETICALLY SIGNIFICANT DOSE

被引:21
作者
NIROOMANDRAD, A
CUMBERLIN, R
机构
[1] Department of Radiation Medicine, Georgetown University Medical Center, Washington, DC, 3800 Reservoir Road, N.W
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1993年 / 25卷 / 04期
关键词
DOSE TO OVARIES AND TESTES; GONADAL DOSE; HODGKIN FIELDS; GENETICALLY SIGNIFICANT DOSE;
D O I
10.1016/0360-3016(93)90023-O
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: To determine the genetically significant dose from therapeutic radiation exposure with Hodgkin's fields by estimating the doses to ovaries and testes. Materials and Methods: Phantom measurements were performed to verify estimated doses to ovaries and testes from Hodgkin's fields. Thermoluminescent LiF dosimeters (TLD-100) of 1 X 3 X 3 mm3 dimensions were embedded in phantoms and exposed to standard mantle and paraaortic fields using Co-60, 4 MV, 6 MV, and 10 MV photon beams. Results: Our results show that measured doses to ovaries and testes are about two to five times higher than the corresponding graphically estimated doses for Co-60 and 4 MVX photon beams as depicted in ICRP publication 44. In addition, the measured doses to ovaries and testes are about 30% to 65% lower for 10 MV photon beams than for their corresponding Co-60 photon beams. Conclusion: The genetically significant dose from Hodgkin's treatment (less than 0.01 mSv) adds about 4% to the genetically significant dose contribution to medical procedures and adds less than 1% to the genetically significant dose from all sources. Therefore, the consequence to society is considered to be very small. The consequences for the individual patient are, likewise, small.
引用
收藏
页码:745 / 751
页数:7
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