GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC STUDY OF LIPIDS AND RAPID DIAGNOSIS OF MYCOBACTERIUM-TUBERCULOSIS

被引：10

作者：

MAYAKOVA, TI

KUZNETSOVA, EE

KOVALEVA, MG

PLYUSNIN, SA

机构：

[1] Irkutsk Institute of Surgery, East-Siberian Scientific Centre, Russian Academy of Medical Sciences

来源：

JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS | 1995年 / 672卷 / 01期

关键词：

D O I：

10.1016/0378-4347(95)00192-L

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The method suggested is based on the identification of tuberculostearic acid as a Mycobacterium tuberculosis marker. Bacterial culture and sputum of patients with pulmonary tuberculosis and lung diseases of non-tuberculous etiology were investigated. A complete coincidence of the results of bacteriological and gas chromatographic-mass spectrometric (GC-MS) methods used in examining a group of patients with pulmonary tuberculosis was found. GC-MS ion monitoring provides a highly sensitive and rapid technique for the diagnosis of pulmonary tuberculosis.

引用

页码：133 / 137

页数：5

共 9 条

[1] DIAGNOSIS OF PULMONARY TUBERCULOSIS BY DETECTION OF TUBERCULOSTEARIC ACID IN SPUTUM BY USING GAS CHROMATOGRAPHY-MASS SPECTROMETRY WITH SELECTED ION MONITORING [J].