BIOCHEMISTRY OF FATTY LIVER AND KIDNEY SYNDROME OF THE FOWL (GALLUS-DOMESTICUS) - METABOLIC EVENTS ASSOCIATED WITH THE ONSET OF THE SYNDROME

1. 1. Susceptible chicks fed on FLKS-inducing diet could die from the syndrome within 7 hr after withdrawal of food. Exceptionally, clinical signs were observed after as little as 0.5-1.5 hr fasting. 2. 2. Liver glycogen was depleted rapidly by fasting in both susceptible and non-susceptible birds and less than 10% remained after 6hr. 3. 3. Plasma glucose in susceptible birds was below physiological levels by 2 hr after removal of food. 4. 4. In susceptible birds, glucose 6-phosphatase activity did not increase on fasting, due apparently to failure of protein synthesis. © 1979.