EFFECTS OF SLEEP-DEPRIVATION ON THE LIMBIC SYSTEM AND THE FRONTAL LOBES IN AFFECTIVE-DISORDERS - A STUDY WITH TC-99M-HMPAO SPECT

被引：156

作者：

EBERT, D ^{[1
]}

FEISTEL, H ^{[1
]}

BAROCKA, A ^{[1
]}

机构：

[1] NUKL MED KLIN,ERLANGEN,GERMANY

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 1991年 / 40卷 / 04期

关键词：

MAJOR DEPRESSION; MELANCHOLIC SUBTYPE; SLEEP DEPRIVATION; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; ANTERIOR PREFRONTAL LOBE; LIMBIC SYSTEM;

D O I：

10.1016/0925-4927(91)90016-J

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied 10 patients with melancholia before and after sleep deprivation and 8 controls with Tc-99m-hexamethylpropylenamineoxime (HMPAO) single photon emission computed tomography (SPECT). All depressed subjects showed relative hypoperfusion in the left anterolateral prefrontal cortex under both conditions. Only responders showed relative hyperperfusion in parts of the limbic system and a reduction of blood flow in these regions after sleep deprivation.

引用

页码：247 / 251

页数：5

共 13 条

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