FUNCTIONAL-ANALYSIS OF THE REGULATORY REGION OF THE YEAST PHOSPHATIDYLSERINE SYNTHASE GENE, PSS

被引：44

作者：

KODAKI, T ^{[1
]}

NIKAWA, JI ^{[1
]}

HOSAKA, K ^{[1
]}

YAMASHITA, S ^{[1
]}

机构：

[1] GUNMA UNIV,SCH MED,DEPT BIOCHEM,MAEBASHI,GUNMA 371,JAPAN

来源：

JOURNAL OF BACTERIOLOGY | 1991年 / 173卷 / 24期

关键词：

D O I：

10.1128/jb.173.24.7992-7995.1991

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The upstream region of the PSS gene contains three positive cis-acting elements, upstream activation sequences 1 and 2 (UAS1 and UAS2) and a TATA box. The 5' end of UAS1 occurs between positions -239 and -209, and that of UAS2 is between positions -172 and -164. UAS2 contains 5'-TTCACATG-3' as a core sequence at positions -161 to -154. Mutational analysis revealed that this octamer is responsible for the control of PSS expression by inositol and choline. The TATA box is located at positions -112 to -108. In addition, PSS contains a negative cis-acting sequence between UAS2 and the TATA box.

引用

页码：7992 / 7995

页数：4

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