NIACIN FOR LIPID DISORDERS - INDICATIONS, EFFECTIVENESS, AND SAFETY

被引：5

作者：

BROWN, WV

机构：

[1] Emory University School of Medicine, 201 Woodruff Memorial Bldg, Atlanta, GA 30322

来源：

POSTGRADUATE MEDICINE | 1995年 / 98卷 / 02期

关键词：

D O I：

10.1080/00325481.1995.11946037

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Niacin can be very effective and safe in lowering low-density lipoprotein cholesterol and triglyceride levels and also in increasing high-density lipoprotein cholesterol levels, In combination with other lipid-lowering drugs (eg, bile acid sequestrants), it has reduced the incidence of cardiovascular events and stopped the progression of coronary artery lesions, It may be the most cost-effective lipid-lowering agent currently available. At lower doses, sustained-release forms of niacin may also improve patient compliance.

引用

收藏

页码：185 / +

页数：1

相关论文

共 36 条

[1] EFFECT OF A MODIFIED, WELL-TOLERATED NIACIN REGIMEN ON SERUM TOTAL CHOLESTEROL, HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AND THE CHOLESTEROL TO HIGH-DENSITY LIPOPROTEIN RATIO [J].

ALDERMAN, JD ;

PASTERNAK, RC ;

SACKS, FM ;

SMITH, HS ;

MONRAD, ES ;

GROSSMAN, W .

AMERICAN JOURNAL OF CARDIOLOGY, 1989, 64 (12) :725-729

[2]

[Anonymous], 1975, JAMA-J AM MED ASSOC, V231, P360

[3]

BAYS HE, 1992, POSTGRAD MED, V91, P162

[4] HYPERCHOLESTEREMIA AND NICOTINIC ACID - A LONG-TERM STUDY [J].

BERGE, KG ;

MASON, HL ;

CHRISTENSEN, NA ;

BARKER, NW ;

ACHOR, RWP .

AMERICAN JOURNAL OF MEDICINE, 1961, 31 (01) :24-&

[5] BENEFICIAL-EFFECTS OF COMBINED COLESTIPOL-NIACIN THERAPY ON CORONARY ATHEROSCLEROSIS AND CORONARY VENOUS BYPASS GRAFTS [J].

BLANKENHORN, DH ;

NESSIM, SA ;

JOHNSON, RL ;

SANMARCO, ME ;

AZEN, SP ;

CASHINHEMPHILL, L .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1987, 257 (23) :3233-3240

[6] REGRESSION OF CORONARY-ARTERY DISEASE AS A RESULT OF INTENSIVE LIPID-LOWERING THERAPY IN MEN WITH HIGH-LEVELS OF APOLIPOPROTEIN-B [J].

BROWN, G ;

ALBERS, JJ ;

FISHER, LD ;

SCHAEFER, SM ;

LIN, JT ;

KAPLAN, C ;

ZHAO, XQ ;

BISSON, BD ;

FITZPATRICK, VF ;

DODGE, HT .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (19) :1289-1298

[7]

BROWN WV, 1990, DRUG TREATMENT HYPER, P189

[8] 15 YEAR MORTALITY IN CORONARY DRUG PROJECT PATIENTS - LONG-TERM BENEFIT WITH NIACIN [J].

CANNER, PL ;

BERGE, KG ;

WENGER, NK ;

STAMLER, J ;

FRIEDMAN, L ;

PRINEAS, RJ ;

FRIEDEWALD, W .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1986, 8 (06) :1245-1255

[9] PRONOUNCED LOWERING OF SERUM LEVELS OF LIPOPROTEIN LP(A) IN HYPERLIPEMIC SUBJECTS TREATED WITH NICOTINIC-ACID [J].

CARLSON, LA ;

HAMSTEN, A ;

ASPLUND, A .

JOURNAL OF INTERNAL MEDICINE, 1989, 226 (04) :271-276

[10] NICOTINIC ACID TREATMENT OF HYPERCHOLESTEREMIA - COMPARISON OF PLAIN AND SUSTAINED-ACTION PREPARATIONS AND REPORT OF 2 CASES OF JAUNDICE [J].

CHRISTENSEN, N ;

MASON, HL ;

BERGE, KG ;

ACHOR, RWP .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1961, 177 (08) :546-&

← 1 2 3 4 →